Honestly, I've found the other stats to be kind of useless.
Strength: I don't really melee, and I have a companion to carry my crap. I often stop at settlements to craft, so I'm rarely overburdened.
Endurance: I'm always above 40 stimpacks, and around 20 med-x. I also have eight suits of power armor, so I can suit up for difficult encounters.
Perception: I don't use VATS very much.
Agility: I have plenty of buffs to sneak already, and often just blow off heads from distance with my .50. Up close and personal I have shotgun that has 120 damage, so no need to sneak around.
Luck: I don't often make use of critical hits, but I suppose I'm missing out on some luck based drops.
That being said, I am looking into pumping some points into strength and melee attacks soon. I just want another way to play.
I'm just annoyingly insistent on making sure the settlements are done right. It's very bothersome to dump an hour into building a nice settlement, but I can't ignore it. Despite this, I still have several that are unoccupied or lacking in various areas. To make anything half decent is just such a drain on resources, and I'm always out of steel. I really wish most walls and floors only cost one or two wood and steel.
Favorite quest so far was easily the one with the Pirate Ship. It was pretty mediocre up until the end, but that kind of sealed the deal. It had the same kind of effect as, "Come Fly With Me," from New Vegas where the neat ending was worth the slog of the rest of the quest. Then again, the only main quests I've done are the Minutemen line, some BoS stuff, and the one where you recruit Strong.