Gravitas - Playing As Female!

A)Character has had a disease since birth, some sort of genetic illness. Some doctors want to try a special, experimental treatment, and it ends up changing his DNA/genes to the other gender. He goes back to school, and from there we deal with the reactions of those around him. What do his old buddies think of their friend now? How do the girls he would flirt with/ask out react to having a new girl around? Maybe the change was more than just a gender change, maybe it affected her sex drive and she's more open to the attention of her old friends/other guys or girls, maybe a teacher is interested to see how far the change went? Lots of room to do stuff with it.

B)I've played something before and want to try it again, that's a bro/sis kind of roleplay. Starting out with two brothers, younger and older, the older always hassling the younger one, as brothers do. They get back at the other by finding a way to turn them into the other gender(science, bitch! Or magic, bitch!). It happens at random, often whenever they get turned on. As for turning back, it could be controlled by the younger brother(an antidote or spell or something), or the only way to turn back is to share an orgasm with someone else(the chemicals produced, or terms of the magic, basically for plot reasons), or maybe something else we come up with! There's the potential for it to become permanent, so that can be messed with or what not. Lots of room to change things and negotiate, bringing in more people to mess with her maybe, any kinks we have could be brought into it to mess with the changed brother. Fun times.

C) I thought about something maybe where a guy volunteers for an experiment, but more gets messed with than he thinks. He gets powers, but has to change genders to use them. Not only that, they get powered when the girl is sexually sated. This could maybe become a superheroine/random people kind of thing where she has to find someone to power her up. Maybe she gets a sidekick to help her out. We can discuss ideas for it.

D) Here's a fan based idea for Dishonored. Basically when Corvo gets his ability from the Outsider, there's a stipulation. He has to change gender, basically because the Outsider thinks it would be fun to watch. We then play through the game, and smut it up as we please, things like Sam wanting a bit of payment for driving the boat, or having Corva sneak into the Golden Cat by pretending to be a worker. Fun stuff.